Making Sense of Mismatch Negativity

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Mismatch negativity

New perspectives in cognitive1,2 and clinical3,4 neuroscience have been opened up with the recent discovery of mismatch negativity (MMN),5 an auditory event-related brain potential (ERP) elicited by infrequent deviant sounds occurring in a sequence of repeated tones.1 The MMN appears as a negative displacement on the ERP to deviant sounds relative to that to standard sounds, with a peak latency...

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The mismatch negativity (MMN) component of the auditory event-related potential has become a valuable tool in cognitive neuroscience. Its reduced size in persons with schizophrenia is of unknown origin but theories proposed include links to problems in experience-dependent plasticity reliant on N-methyl-d-aspartate glutamate receptors. In this review we address the utility of this tool in revea...

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ژورنال

عنوان ژورنال: Frontiers in Psychiatry

سال: 2020

ISSN: 1664-0640

DOI: 10.3389/fpsyt.2020.00468